Concepedia

Discovery of GS-9451: An acid inhibitor of the hepatitis C virus NS3/4A protease

X. Christopher Sheng, T.C. Appleby, Thomas Butler, Ruby Cai, Xiaowu Chen, Aesop Cho, Michael O. Clarke, Jeromy J. Cottell, William E. Delaney, Edward Doerffler,

Bioorganic & Medicinal Chemistry Letters · 2012 · 42 citations · 9 references

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9

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

Qui‐Lim Choo, George Kuo, Amy J. Weiner et al. · Science · 1989 · 6.9K citations

, , +15

Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection

Ira M. Jacobson, John G. McHutchison, Geoffrey Dusheiko et al. · New England Journal of Medicine · 2011 · 2.4K citations · Full text

An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

Daniel Lamarre, Paul C. Anderson, Murray D. Bailey et al. · Nature · 2003 · 911 citations

, , +9

Rapid Decline of Viral RNA in Hepatitis C Patients Treated With VX-950: A Phase Ib, Placebo-Controlled, Randomized Study

Hendrik W. Reesink, Stefan Zeuzem, Christine J. Weegink et al. · Gastroenterology · 2006 · 394 citations

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SCH 503034, a Mechanism-Based Inhibitor of Hepatitis C Virus NS3 Protease, Suppresses Polyprotein Maturation and Enhances the Antiviral Activity of Alpha Interferon in Replicon Cells

Bruce A. Malcolm, R. Liu, Frederick Lahser et al. · Antimicrobial Agents and Chemotherapy · 2006 · 316 citations · Full text

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