Publication | Open Access

Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Hematological MalignancySecondary D835y MutationEngineeringMixed-phenotype Acute LeukemiaMalignant Blood DisorderHematologyClinical Resistance PatternsMyeloid NeoplasiaSelective Flt3 InhibitionMolecular DiagnosticsSystems BiologyOncologyRadiation OncologyCancer ResearchHealth Sciences