Amir Faisal

The regulated assembly of a PKCɛ complex controls the completion of cytokinesis

Adrian T. Saurin, Joanne Durgan, Angus J.M. Cameron et al. · Nature Cell Biology · 2008 · 124 citations

Pkcɛ Complex, Signal Transduction, Cell Regulation +11

Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Andrew S. Moore, Amir Faisal, David González de Castro et al. · Leukemia · 2012 · 118 citations · Full text

Hematological Malignancy, Secondary D835y Mutation, Engineering +12

Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA

Malgorzata Kisielow, Sandra Kleiner, Michiaki Nagasawa et al. · Biochemical Journal · 2002 · 88 citations · Full text

Engineering, Individual Isoforms, Genetics +20

The Aurora Kinase Inhibitor CCT137690 Downregulates MYCN and Sensitizes <i>MYCN</i> -Amplified Neuroblastoma <i>In Vivo</i>

Amir Faisal, Lynsey Vaughan, Vassilios Bavetsias et al. · Molecular Cancer Therapeutics · 2011 · 82 citations · Full text

Imidazo[4,5-<i>b</i>]pyridine Derivatives As Inhibitors of Aurora Kinases: Lead Optimization Studies toward the Identification of an Orally Bioavailable Preclinical Development Candidate

Vassilios Bavetsias, Jonathan M. Large, Chongbo Sun et al. · Journal of Medicinal Chemistry · 2010 · 81 citations · Full text