Paul Workman

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 1.9K citations · Full text

Guidelines for the welfare and use of animals in cancer research

Paul Workman, Eric O. Aboagye, Frances R. Balkwill et al. · British Journal of Cancer · 2010 · 1.4K citations · Full text

Cancer Management, Animal Welfare, Pathology +17

The Identification of 2-(1<i>H</i>-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-<i>d</i>]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer

Adrian Folkes, Khatereh Ahmadi, W. Alderton et al. · Journal of Medicinal Chemistry · 2008 · 739 citations · Full text

Pi3 Kinase, Chemoprevention Strategy, Pharmacotherapy +18

Activation of the ATPase Activity of Hsp90 by the Stress-Regulated Cochaperone Aha1

Barry Panaretou, Giuliano Siligardi, Philippe Meyer et al. · Molecular Cell · 2002 · 541 citations · Full text

Atpase Activity, Reductive Stress, Signal Transduction +10

The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

Martin O. Leach, Kevin M. Brindle, Jeff Evelhoch et al. · British Journal of Cancer · 2005 · 511 citations · Full text

Vascular Disease, Engineering, Oncologic Imaging +25