Paul Workman

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 2.1K citations · Full text

Medicine, Oncology, Pharmacology +17

Guidelines for the welfare and use of animals in cancer research

Paul Workman, Eric O. Aboagye, Frances R. Balkwill et al. · British Journal of Cancer · 2010 · 1.4K citations · Full text

Medicine, Animal Sciences, Oncology +17

The Identification of 2-(1<i>H</i>-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-<i>d</i>]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer

Adrian Folkes, Khatereh Ahmadi, W. Alderton et al. · Journal of Medicinal Chemistry · 2008 · 746 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Activation of the ATPase Activity of Hsp90 by the Stress-Regulated Cochaperone Aha1

Barry Panaretou, Giuliano Siligardi, Philippe Meyer et al. · Molecular Cell · 2002 · 548 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

Martin O. Leach, Kevin M. Brindle, Jeff Evelhoch et al. · British Journal of Cancer · 2005 · 514 citations · Full text

Medicine, Oncology, Radiology +17