Concepedia

Interferons Direct Th2 Cell Reprogramming to Generate a Stable GATA-3+T-bet+ Cell Subset with Combined Th2 and Th1 Cell Functions

Ahmed N. Hegazy, Caroline Helmstetter, Isabel Panse, Anja Fröhlich, Andreas Bergthaler, Lukas Flatz, Daniel D. Pinschewer, Andreas Radbruch, Max Löhning

Immunity · 2010 · 333 citations · 44 references

DOIFull text

Open access

Concepts

References

44

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

, , +13

Functional Role of Type I and Type II Interferons in Antiviral Defense

Ulrike Müller, Ulrich Steinhoff, Luiz F. L. Reis et al. · Science · 1994 · 2.5K citations · Full text

, , +15

The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells

Wei-ping Zheng, Richard A. Flavell · Cell · 1997 · 2.4K citations · Full text

, , +17

Plasticity of CD4+ T Cell Lineage Differentiation

Liang Zhou, Mark M. W. Chong, Dan R. Littman · Immunity · 2009 · 1.5K citations · Full text

, , +11

Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset

Marc Veldhoen, Catherine Uyttenhove, Jacques Van Snick et al. · Nature Immunology · 2008 · 1.2K citations

, , +14