Concepedia

Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

Weiping Cao, Santhakumar Manicassamy, Hua Tang, Sudhir Pai Kasturi, Ali Pirani, Niren Murthy, Bali Pulendran

Nature Immunology · 2008 · 388 citations · 19 references

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References

19

Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway

Masahiro Yamamoto, Shintaro Sato, Hiroaki Hemmi et al. · Science · 2003 · 3.2K citations

, , +17

IRF-7 is the master regulator of type-I interferon-dependent immune responses

Kenya Honda, Hideyuki Yanai, Hideo Negishi et al. · Nature · 2005 · 2.2K citations

, , +13

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

Eicke Latz, Annett Schoenemeyer, Alberto Visintin et al. · Nature Immunology · 2004 · 1.3K citations

, , +6

Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction

Mitsuharu Sato, Hirofumi Suemori, Naoki Hata et al. · Immunity · 2000 · 1.3K citations · Full text

, , +16

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Taro Kawai, Shintaro Sato, Ken J. Ishii et al. · Nature Immunology · 2004 · 1K citations

, , +16