Concepedia

N-Acyl-l-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation

Li Chen, Jefferson Tilley, Richard Trilles, Weiya Yun, David C. Fry, Charles M. Cook, Karen Rowan, Virginia Schwinge, Robert M. Campbell

Bioorganic & Medicinal Chemistry Letters · 2002 · 25 citations · 7 references

DOIFull text

Open access

Concepts

References

7

Preparation and use of C2-symmetric bis(phospholanes): production of .alpha.-amino acid derivatives via highly enantioselective hydrogenation reactions

Mark J. Burk, John E. Feaster, William A. Nugent et al. · Journal of the American Chemical Society · 1993 · 602 citations

, , +12

Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses

Ko‐Chung Lin, Humayun S. Ateeq, Sherry H Hsiung et al. · Journal of Medicinal Chemistry · 1999 · 207 citations · Full text

, , +17

Potent α4β1 Peptide Antagonists as Potential Anti-Inflammatory Agents

David Y. Jackson, Clifford Quan, Dean R. Artis et al. · Journal of Medicinal Chemistry · 1997 · 80 citations · Full text

, , +17

N-Benzylpyroglutamyl-l-phenylalanine derivatives as VCAM/VLA-4 antagonists

Li Chen, Jefferson Tilley, Robert Guthrie et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 32 citations · Full text

, , +4

Imide and lactam derivatives of N-benzylpyroglutamyl-l-phenylalanine as VCAM/VLA-4 antagonists

Jefferson Tilley, Gerry Kaplan, Virginia Schwinge et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 21 citations · Full text

, , +4