Clifford Quan

A Designed Peptide Ligase for Total Synthesis of Ribonuclease A with Unnatural Catalytic Residues

David Y. Jackson, John P. Burnier, Clifford Quan et al. · Science · 1994 · 284 citations

Bioorganic Chemistry, Engineering, Engineered Variant +18

Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation

Ingrid E. Wertz, Kim Newton, Dhaya Seshasayee et al. · Nature · 2015 · 251 citations

Inflammation, Anti-inflammatory, Autoimmune Disease +7

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

John A. Flygare, Maureen H. Beresini, Nageshwar Budha et al. · Journal of Medicinal Chemistry · 2012 · 247 citations · Full text

Apoptosis, Cell Death, Clinical Candidate +20

Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation

Xiaolei Ma, Elizabeth Helgason, Qui Phung et al. · Proceedings of the National Academy of Sciences · 2012 · 226 citations · Full text

Immune Regulation, Immunology, Tank-binding Kinase +21

Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

Wayne J. Fairbrother, Hans W. Christinger, Andrea G. Cochran et al. · Biochemistry · 1998 · 190 citations