Concepedia

Proteasome Active Sites Allosterically Regulate Each Other, Suggesting a Cyclical Bite-Chew Mechanism for Protein Breakdown

Alexei F. Kisselev, Tatos Akopian, Vanesa Castillo, Alfred L. Goldberg

Molecular Cell · 1999 · 291 citations · 26 references

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26

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

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Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

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Structure of 20S proteasome from yeast at 2.4Å resolution

M. Groll, Lars Ditzel, Jan Löwe et al. · Nature · 1997 · 2.3K citations

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A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson et al. · Journal of Biological Chemistry · 1997 · 2.1K citations · Full text

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The Sizes of Peptides Generated from Protein by Mammalian 26 and 20 S Proteasomes

Alexei F. Kisselev, Tatos Akopian, Kee Min Woo et al. · Journal of Biological Chemistry · 1999 · 576 citations · Full text

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