Concepedia

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer

Troels B. Jensen, Jonas R. Henriksen, Bjarne E. Rasmussen, Lars Melholt Rasmussen, Thomas L. Andresen, Jesper Wengel, Anna Pasternak

Bioorganic & Medicinal Chemistry · 2011 · 47 citations · 26 references

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References

26

Selection of single-stranded DNA molecules that bind and inhibit human thrombin

Louis C. Bock, Linda C. Griffin, John Latham et al. · Nature · 1992 · 2.5K citations

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Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution.

Román F. Macaya, Peter Schultze, F. W. Smith et al. · Proceedings of the National Academy of Sciences · 1993 · 877 citations · Full text

, , +17

The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.

K. Padmanabhan, K. Padmanabhan, Joseph D. Ferrara et al. · Journal of Biological Chemistry · 1993 · 462 citations · Full text

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Thermal difference spectra: a specific signature for nucleic acid structures

Jean‐Louis Mergny · Nucleic Acids Research · 2005 · 456 citations · Full text

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THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER

K. Padmanabhan, K. Padmanabhan, Joseph D. Ferrara et al. · 1993 · 427 citations

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