Anna Pasternak

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

Anna Pasternak, Frank J. Hernández, Lars Melholt Rasmussen et al. · Nucleic Acids Research · 2010 · 174 citations · Full text

Protein Assembly, Molecular Biology, Nucleic Acid Amplification Test +17

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

Niels Langkjær, Anna Pasternak, Jesper Wengel · Bioorganic & Medicinal Chemistry · 2009 · 143 citations

Nucleic Acid Chemistry, Engineering, Natural Sciences +8

Thermodynamics of RNA duplexes modified with unlocked nucleic acid nucleotides

Anna Pasternak, Jesper Wengel · Nucleic Acids Research · 2010 · 58 citations · Full text

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative

Weronika Kotkowiak, Jolanta Lisowiec‐Wąchnicka, Jakub Grynda et al. · Molecular Therapy — Nucleic Acids · 2017 · 52 citations · Full text

Thrombopoiesis, Thrombosis, Medicinal Chemistry +10

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer

Troels B. Jensen, Jonas R. Henriksen, Bjarne E. Rasmussen et al. · Bioorganic & Medicinal Chemistry · 2011 · 47 citations · Full text

Nucleic Acid Chemistry, Biochemistry, 2′-C-piperazino-una Monomer +7