Concepedia

Aptamer Biophysics

Aptamer Biophysics is a specialized subfield of nucleic acid biophysics that investigates the structural, thermodynamic, and dynamic properties of aptamers—single-stranded DNA or RNA molecules that adopt specific three-dimensional conformations to selectively bind molecular targets—thereby elucidating the biophysical principles underlying their recognition, stability, and function.

92

Publications

5.6K

Citations

382

Authors

154

Institutions

Publications per year

2017–2026

28

Parents

Publications

92

Three-dimensional Solution Structure of the Thrombin-binding DNA Aptamer d(GGTTGGTGTGGTTGG)

Peter Schultze, Román F. Macaya, Juli Feigon · Journal of Molecular Biology · 1994 · 406 citations

, , +13

Folding of the Thrombin Aptamer into a G-Quadruplex with Sr<sup>2+</sup>:  Stability, Heat, and Hydration

Besik Kankia, Luis A. Marky · Journal of the American Chemical Society · 2001 · 300 citations

, , +17

Thermodynamic and Kinetic Characterization of Ligand Binding to the Purine Riboswitch Aptamer Domain

S.D. Gilbert, Colby D. Stoddard, Sarah Wise et al. · Journal of Molecular Biology · 2006 · 264 citations

, , +16

A DNA‐Based Machine That Can Cyclically Bind and Release Thrombin

Wendy U. Dittmer, Andreas Reuter, Friedrich C. Simmel · Angewandte Chemie International Edition · 2004 · 255 citations

, , +15

Optical Thermophoresis for Quantifying the Buffer Dependence of Aptamer Binding

Philipp Baaske, Christoph J. Wienken, Philipp Reineck et al. · Angewandte Chemie International Edition · 2010 · 245 citations

, , +17

1–5 of 92

Authors

382

  1. GG
    Giridharan Gokulrangan

    Case Western Reserve University, United States

    4 publications · 206 citations

    4

    h-index

  2. PE
    Philip E. Johnson

    York University, Canada

    4 publications · 267 citations

    4

    h-index

  3. CK
    Carey K. Johnson

    University of Kansas, United States

    4 publications · 206 citations

    4

    h-index

  4. JR
    Jay R. Unruh

    Stowers Institute for Medical Research, United States

    4 publications · 206 citations

    4

    h-index

  5. MA
    Miguel A. D. Neves

    University of Toronto, Canada

    3 publications · 253 citations

    3

    h-index

1–5 of 382

Institutions

154

  1. Goethe University Frankfurt

    Frankfurt am Main, Germany

    5 h-index

    13 publications

    394 citations

  2. York University

    Toronto, Canada

    4 h-index

    15 publications

    958 citations

  3. University of Colorado Boulder

    Boulder, United States

    3 h-index

    10 publications

    1.9K citations

  4. University of Kansas

    Lawrence, United States

    3 h-index

    10 publications

    632 citations

  5. University of Bonn

    Bonn, Germany

    3 h-index

    13 publications

    781 citations

  6. University of Naples Federico II

    Naples, Italy

    3 h-index

    15 publications

    848 citations

  7. Institute of Biostructure and Bioimaging

    Naples, Italy

    3 h-index

    6 publications

    371 citations

  8. National Center for Nanoscience and Technology

    Beijing, China

    2 h-index

    2 publications

    118 citations

1–8 of 154

Venues

  1. Journal of Molecular Biology

    JMB · 5 publications · 939 citations

    5

    h-index

  2. Nucleic Acids Research

    4 publications · 243 citations

    4

    h-index

  3. Journal of Molecular Graphics and Modelling

    4 publications · 89 citations

    4

    h-index

  4. The Journal of Physical Chemistry B

    4 publications · 120 citations

    4

    h-index

  5. Journal of the American Chemical Society

    JACS · 4 publications · 467 citations

    4

    h-index

1–5