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A Strategy for High-Throughput Assay Development Using Leads Derived from Nuclear Magnetic Resonance-Based Screening

Philip J. Hajduk, Stephen F. Betz, J. Mack, Xiaoan Ruan, Danli L. Towne, Claude G. Lerner, Bruce A. Beutel, Stephen W. Fesik

SLAS DISCOVERY · 2002 · 23 citations · 9 references

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9

Pure absorption gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity

Paul A. Keifer, Tim Saarinen · Journal of the American Chemical Society · 1992 · 2.3K citations

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An exact mathematical expression for describing competitive binding of two different ligands to a protein molecule

Zhixin Wang · FEBS Letters · 1995 · 374 citations

, , +17

NMR-Based Screening of Proteins Containing <sup>13</sup>C-Labeled Methyl Groups

Philip J. Hajduk, David J. Augeri, J. Mack et al. · Journal of the American Chemical Society · 2000 · 207 citations

, , +14

High-Throughput Nuclear Magnetic Resonance-Based Screening

Philip J. Hajduk, Tobias Gerfin, Jean-Marc Boehlen et al. · Journal of Medicinal Chemistry · 1999 · 183 citations

, , +17

Minimizing Sensitivity Losses in Gradient-Selected 15N-1H HSQC Spectra of Proteins

Jonathan Stonehouse, Graeme L. Shaw, James Keeler et al. · Journal of Magnetic Resonance Series A · 1994 · 134 citations

, , +7