Concepedia

High-throughput Functional Screening

High-Throughput Functional Screening is a systematic experimental approach that belongs to the class of functional genomics methodologies and is distinguished by its capacity to rapidly and simultaneously assess the biological functions of a large number of genes, proteins, or genetic variants using automated, scalable assays.

377

Publications

23.2K

Citations

3K

Authors

780

Institutions

Publications per year

2017–2026

127

Variants

Htfs

Parents

Publications

377

Growth Stage-Based Phenotypic Analysis of Arabidopsis: A Model for High Throughput Functional Genomics in Plants

D. C. Boyes · The Plant Cell · 2001 · 842 citations

, , +13

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

Yuexin Zhou, Shiyou Zhu, Changzu Cai et al. · Nature · 2014 · 762 citations

, , +17

Signal Transduction in Maize and Arabidopsis Mesophyll Protoplasts

Jen Sheen · PLANT PHYSIOLOGY · 2001 · 685 citations

, , +17

Simultaneous assay of every <i>Salmonella</i> Typhi gene using one million transposon mutants

Gemma C. Langridge, Minh‐Duy Phan, Daniel J. Turner et al. · Genome Research · 2009 · 655 citations · Full text

, , +17

CRISPR–Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome

Tyler S. Klann, Joshua B. Black, Malathi Chellappan et al. · Nature Biotechnology · 2017 · 470 citations · Full text

, , +16

1–5 of 377

Authors

3K

  1. LJ
    Luis J. V. Galietta

    Istituto Giannina Gaslini, Italy

    6 publications · 411 citations

    6

    h-index

  2. HM
    Hiroyuki Mano

    Jichi Medical University, Japan

    5 publications · 444 citations

    5

    h-index

  3. SK
    Shinji Kohsaka

    The University of Tokyo, Japan

    5 publications · 444 citations

    5

    h-index

  4. TU
    Toshihide Ueno

    The University of Tokyo, Japan

    4 publications · 232 citations

    4

    h-index

  5. MI
    Masachika Ikegami

    Tokyo Metropolitan Komagome Hospital, Japan

    3 publications · 153 citations

    3

    h-index

1–5 of 3K

Institutions

780

  1. Harvard University

    Cambridge, United States

    16 h-index

    85 publications

    5.1K citations

  2. University of California San Diego

    San Diego, United States

    12 h-index

    49 publications

    3.6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    44 publications

    4.6K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    16 publications

    1.3K citations

  5. University of California, San Francisco

    San Francisco, United States

    9 h-index

    27 publications

    3.1K citations

  6. Massachusetts General Hospital

    Boston, United States

    8 h-index

    12 publications

    1.1K citations

  7. Inserm

    Paris, France

    7 h-index

    44 publications

    2.3K citations

  8. Heidelberg University

    Heidelberg, Germany

    6 h-index

    28 publications

    2.4K citations

1–8 of 780

Venues

  1. SLAS DISCOVERY

    26 publications · 908 citations

    17

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 14 publications · 1.4K citations

    14

    h-index

  3. Scientific Reports

    12 publications · 331 citations

    12

    h-index

  4. Nature Communications

    11 publications · 836 citations

    11

    h-index

  5. PLoS ONE

    12 publications · 383 citations

    11

    h-index

1–5