Toshihide Ueno

EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors

Young Lim Choi, Manabu Soda, Yoshihiro Yamashita et al. · New England Journal of Medicine · 2010 · 1.2K citations · Full text

Pathology, Fusion-type Tyrosine Kinase, Cancer Biology +16

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 785 citations

Cancer Immunosurveillance, Autoimmune Disease, T-regulatory Cell +12

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer

Kengo Takeuchi, Young Lim Choi, Yuki Togashi et al. · Clinical Cancer Research · 2009 · 711 citations

A mouse model for <i>EML4-ALK</i> -positive lung cancer

Manabu Soda, Shuji Takada, Kengo Takeuchi et al. · Proceedings of the National Academy of Sciences · 2008 · 509 citations · Full text

Fusion Kinase, Human Eml4-alk Form, Tumor Microenvironment +15