A novel protective mechanism for mitochondrial aldehyde dehydrogenase (ALDH2) in type i diabetes-induced cardiac dysfunction: Role of AMPK-regulated autophagy

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 6.8K citations · Full text

Mtor Regulate Autophagy, Mitophagy, Cell Autophagy +10

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Atsuko Nakai, Osamu Yamaguchi, Toshihiro Takeda et al. · Nature Medicine · 2007 · 1.5K citations

Mechanobiology, Cardiac Muscle, Mitophagy +13

Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion

Yutaka Matsui, Hiromitsu Takagi, Xueping Qu et al. · Circulation Research · 2007 · 1.5K citations

Mitophagy, Heart Failure, Cardiovascular Function +20

3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

Per O. Seglen, Paul B. Gordon · Proceedings of the National Academy of Sciences · 1982 · 1.3K citations · Full text

Specific Inhibitor, Mitophagy, Amino Acids +26

Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart

Che-Hong Chen, Grant R. Budas, Eric N. Churchill et al. · Science · 2008 · 761 citations · Full text

Heart Failure, Ischemia-induced Cardiac Damage, Lipid Peroxidation +16