Toshihiro Takeda

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Atsuko Nakai, Osamu Yamaguchi, Toshihiro Takeda et al. · Nature Medicine · 2007 · 1.5K citations

Mechanobiology, Cardiac Muscle, Mitophagy +13

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi et al. · Nature · 2012 · 1.1K citations

Cell Autophagy, Mitophagy, Heart Failure +11

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

Tomokazu Murakawa, Osamu Yamaguchi, Ayako Hashimoto et al. · Nature Communications · 2015 · 494 citations · Full text

Inhibition of autophagy in the heart induces age-related cardiomyopathy

Manabu Taneike, Osamu Yamaguchi, Atsuko Nakai et al. · Autophagy · 2010 · 446 citations

p38α Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload

Kazuhiko Nishida, Osamu Yamaguchi, Shinichi Hirotani et al. · Molecular and Cellular Biology · 2004 · 230 citations · Full text

Cardiac Muscle, Heart Failure, Cardiomyocyte Survival +19