Shinichi Hirotani

Involvement of Nuclear Factor-κB and Apoptosis Signal-Regulating Kinase 1 in G-Protein–Coupled Receptor Agonist–Induced Cardiomyocyte Hypertrophy

Shinichi Hirotani, Kinya Otsu, Kazuhiko Nishida et al. · Circulation · 2002 · 360 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

Type 5 Adenylyl Cyclase Disruption Increases Longevity and Protects Against Stress

Lin Yan, Dorothy E. Vatner, J. Patrick O’Connor et al. · Cell · 2007 · 351 citations · Full text

Education, Cell Biology, Molecular Biology +14

p38α Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload

Kazuhiko Nishida, Osamu Yamaguchi, Shinichi Hirotani et al. · Molecular and Cellular Biology · 2004 · 234 citations · Full text

Life Sciences, Molecular Biology, Physiology +14

Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

Osamu Yamaguchi, Yoshiharu Higuchi, Shinichi Hirotani et al. · Proceedings of the National Academy of Sciences · 2003 · 227 citations · Full text

Life Sciences, Cardiology, Cell Biology +15

Involvement of Reactive Oxygen Species-mediated NF- κ B Activation in TNF- α -induced Cardiomyocyte Hypertrophy

Yoshiharu Higuchi, Kinya Otsu, Kazuhiko Nishida et al. · Journal of Molecular and Cellular Cardiology · 2002 · 194 citations

Life Sciences, Cardiology, Physiology +14