Kinya Otsu

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature · 2006 · 3.8K citations

Rig-i Helicases, Virus Structure, Viral Replication +11

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Takashi Nakagawa, Shigeomi Shimizu, Tetsuya Watanabe et al. · Nature · 2005 · 1.6K citations

Inflammation, Mitophagy, Biochemistry +9

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

Atsuko Nakai, Osamu Yamaguchi, Toshihiro Takeda et al. · Nature Medicine · 2007 · 1.5K citations

Mechanobiology, Cardiac Muscle, Mitophagy +13

Identification of a Mutation in Porcine Ryanodine Receptor Associated with Malignant Hyperthermia

Junichi Fujii, Kinya Otsu, Francesco Zorzato et al. · Science · 1991 · 1.5K citations

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi et al. · Nature · 2012 · 1.1K citations

Cell Autophagy, Mitophagy, Heart Failure +11