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6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors

Jiaqiang Cai, Mark Baugh, Darcey Black, Clive Long, David Jonathan Bennett, Maureen Dempster, Xavier Fradera, Jonathan Gillespie, Fiona Andrews, Sylviane Boucharens,

Bioorganic & Medicinal Chemistry Letters · 2010 · 17 citations · 16 references

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16

Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain

Anna K. Clark, Ping K. Yip, John Grist et al. · Proceedings of the National Academy of Sciences · 2007 · 481 citations · Full text

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Novel Purine Nitrile Derived Inhibitors of the Cysteine Protease Cathepsin K

Eva Altmann, Sandra W. Cowan‐Jacob, Martin Missbach · Journal of Medicinal Chemistry · 2004 · 72 citations · Full text

, , +12

Identification of a Potent and Selective Noncovalent Cathepsin S Inhibitor

Robin L. Thurmond, Siquan Sun, Clark A. Sehon et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 55 citations

, , +17

Novel scaffold for cathepsin K inhibitors

Naoki Teno, Takahiro Miyake, Takeru Ehara et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 41 citations · Full text

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Discovery of Orally Bioavailable Cathepsin S Inhibitors for the Reversal of Neuropathic Pain

Osamu Irie, Takatoshi Kosaka, Takeru Ehara et al. · Journal of Medicinal Chemistry · 2008 · 39 citations · Full text

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