Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides 1 1Edited by I. A. Wilson

Achim Knappik, Liming Ge, Annemarie Honegger et al. · Journal of Molecular Biology · 2000 · 731 citations

Immunocytochemical Technique, Engineering, Modular Consensus Frameworks +12

Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured fab in complex with antigen 1 1Edited by I. A. Wilson

Yvonne Chen, Christian Wiesmann, Germaine Fuh et al. · Journal of Molecular Biology · 1999 · 446 citations

Crystal Structure, Affinity-matured Fab, Immunology +6

Phase II Study of Rituximab in Combination With CHOP Chemotherapy in Patients With Previously Untreated, Aggressive Non-Hodgkin’s Lymphoma

Julie M. Vose, Brian K. Link, Michael L. Grossbard et al. · Journal of Clinical Oncology · 2001 · 416 citations

Isolation of Picomolar Affinity Anti-c-erbB-2 Single-chain Fv by Molecular Evolution of the Complementarity Determining Regions in the Center of the Antibody Binding Site

Robert Schier, Adrian M. McCall, Gregory P. Adams et al. · Journal of Molecular Biology · 1996 · 381 citations

Immunocytochemical Technique, Complementarity Determining Regions, Immunology +7

Effects of CAMPATH-1 antibodies in vivo in patients with lymphoid malignancies: influence of antibody isotype

G Hale, F. G. J. Hayhoe, Herman Waldmann · Blood · 1989 · 347 citations