Concepedia

Elevated Frequencies of Circulating Th22 Cell in Addition to Th17 Cell and Th17/Th1 Cell in Patients with Acute Coronary Syndrome

Lei Zhang, Ting Wang, Xiaoqi Wang, DU Rui-zhi, Kaining Zhang, Xinguang Liu, Daoxin Ma, Shuang Yu, Zhenhua Li, Yuqing Guan,

PLoS ONE · 2013 · 41 citations · 43 references

DOIFull text

Open access

Abstract

Our findings showed increased frequencies of both Th22 and Th17 cells in ACS patients, which suggest that Th22 and Th17 cells may play a potential role in plaque destabilization and the development of ACS.

References

43

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5K citations · Full text

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

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Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Yan Zheng, Dimitry M. Danilenko, Patricia Valdez et al. · Nature · 2006 · 1.8K citations

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Phenotypic and functional features of human Th17 cells

Francesco Annunziato, Lorenzo Cosmi, Veronica Santarlasci et al. · The Journal of Experimental Medicine · 2007 · 1.8K citations · Full text

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

Thomas Duhen, Rebekka Geiger, David Jarrossay et al. · Nature Immunology · 2009 · 1K citations

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