Immune-mediated inflammatory diseases is a broad classification of chronic disorders characterized by dysregulated immune responses that drive persistent inflammation and subsequent tissue damage. As a research concept, it investigates the complex interplay of genetic, environmental, and immunological factors underlying disease pathogenesis, exploring the specific cellular and molecular pathways involved in the immune system's aberrant targeting of host tissues. Key characteristics include the involvement of adaptive and/or innate immune cells, production of inflammatory mediators, and diverse clinical manifestations depending on the affected organ systems. Its significance as a field lies in addressing a substantial global health burden, necessitating advanced understanding for the development of effective diagnostic biomarkers and targeted therapeutic interventions.