Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors

On the Origin of Cancer Cells

Otto Warbürg · Science · 1956 · 13.1K citations

Human Cell, Months1,079total Citations9,249last 6, Engineering +13

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

Valeria R. Fantin, Julie St‐Pierre, Philip Leder · Cancer Cell · 2006 · 1.6K citations · Full text

Tumor Biology, Mitochondrial Function, Biochemistry +12

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Anne Le, Charles R. Cooper, Arvin M. Gouw et al. · Proceedings of the National Academy of Sciences · 2010 · 1.5K citations · Full text

Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol

Ming Zhou, Yuhua Zhao, Yan Ding et al. · Molecular Cancer · 2010 · 382 citations · Full text

Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level

Qianru Yu, Ahmed A. Heikal · Journal of Photochemistry and Photobiology B Biology · 2008 · 281 citations · Full text

Single-cell Level, Engineering, Novel Imaging Method +14