Anne Le

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Anne Le, Charles R. Cooper, Arvin M. Gouw et al. · Proceedings of the National Academy of Sciences · 2010 · 1.5K citations · Full text

Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells

Anne Le, Andrew N. Lane, Max Hamaker et al. · Cell Metabolism · 2012 · 1.1K citations · Full text

Signal Transduction, Glucose-independent Glutamine Metabolism, Biochemistry +11

Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC

Wei Liu, Anne Le, Chad N. Hancock et al. · Proceedings of the National Academy of Sciences · 2012 · 460 citations · Full text

Proline Oxidase, Proline Biosynthesis, Metabolic Remodeling +22

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

Yan Xiang, Zachary E. Stine, Jinsong Xia et al. · Journal of Clinical Investigation · 2015 · 390 citations · Full text

Chemoprevention Strategy, Immunology, Gls Inhibitors +16

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

Liyang Cui, Arvin M. Gouw, Edward L. LaGory et al. · Nature Biotechnology · 2020 · 325 citations · Full text

Tumor Biology, Breast Oncology, Mitochondrial Function +6