Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

Svetlana Mojsov, G. Heinrich, Ira B. Wilson, +3

Journal of Biological Chemistry

GeneticsGlycobiologyGastroenterologyGastrointestinal Peptide HormoneProtein Expression +18

Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

Cathrine Ørskov, Jens J. Holst, Svend Knuhtsen, +3

Endocrinology

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

Timothy F. Gallagher, George Seibel, Shouki Kassis, +20

Bioorganic & Medicinal Chemistry

InflammationCytokineReductive StressSignal TransductionCell Regulation +13

Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase

Nigel J. Liverton, John W. Butcher, Christopher F. Claiborne, +28

Journal of Medicinal Chemistry

ImmunologyPharmacotherapyChemical BiologyPharmaceutical ChemistryInflammation +15

Potent, orally absorbed glucagon receptor antagonists

Stephen E. de Laszlo, Candice Hacker, Bing Li, +8

Bioorganic & Medicinal Chemistry Letters

G Protein-coupled ReceptorMedicineFunctional SelectivityPhysiologyPharmacotherapy +3

Kinetic Mechanism for p38 MAP Kinase

Philip V. LoGrasso, Betsy Frantz, Anna Rolando, +3

Biochemistry

InflammationMolecular PhysiologySignal TransductionBiochemistryP38 Map Kinase +13

Synthetic peptide antagonists of glucagon.

Cecilia G. Unson, David Andreu, Ellen Gurzenda, +1

Proceedings of the National Academy of Sciences

GlycobiologyPeptide SciencePeptide TherapeuticsGastrointestinal Peptide HormoneSeveral Glucagon Analogs +14

Molecular and cellular aspects of the glucagon receptor: role in diabetes and metabolism.

Rémy Burcelin, Ellen B. Katz, Maureen Charron

PubMed

Discovery and Structure−Activity Relationship of the First Non-Peptide Competitive Human Glucagon Receptor Antagonists

Peter Madsen, Lotte Bjerre Knudsen, Finn C. Wiberg, +1

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryDrug TargetBiochemistryFunctional Selectivity +13

Characterization of a Novel, Non-peptidyl Antagonist of the Human Glucagon Receptor

Margaret A. Cascieri, Gregory Koch, Elżbieta Ber, +8

Journal of Biological Chemistry