Potent, orally absorbed glucagon receptor antagonists

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

John C. Lee, Jeffrey T. Laydon, Peter McDonnell et al. · Nature · 1994 · 3.3K citations

Inflammation, Cytokine, Signal Transduction +13

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

Svetlana Mojsov, G. Heinrich, Ira B. Wilson et al. · Journal of Biological Chemistry · 1986 · 710 citations · Full text

Genetics, Glycobiology, Gastroenterology +20

Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

Cathrine Ørskov, Jens J. Holst, Svend Knuhtsen et al. · Endocrinology · 1986 · 488 citations

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

Liang Tong, Susan Pav, Della White et al. · Nature Structural Biology · 1997 · 386 citations

Specific Inhibitor, Signal Transduction, Signaling Pathway +11

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

Keith P. Wilson, Patricia G. McCaffrey, Kathy Hsiao et al. · Chemistry & Biology · 1997 · 275 citations · Full text

Drug Target, P38 Map Kinase, Biochemistry +10