A functional inflammasome activation assay differentiates patients with pathogenic NLRP3 mutations and symptomatic patients with low penetrance variants

References

Page 1

	Year	Citations
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression Franz Bauernfeind, Gábor Horváth, Andrea Stutz, The Journal of Immunology	2009	2.8K
NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder Laetitia Agostini, Fabio Martinon, Kimberly Burns, Immunity InflammationMuckle-wells Autoinflammatory DisorderIl-1β-processing InflammasomeImmunologyChronic Inflammation	2004	1.7K
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome Hal M. Hoffman, James L. Mueller, David H. Broide, Nature Genetics Mendelian DisorderDisease MechanismGenetic DisorderGeneticsNew Gene	2001	1.6K
Use of Canakinumab in the Cryopyrin-Associated Periodic Syndrome Helen J. Lachmann, Isabelle Koné‐Paut, Jasmin Kuemmerle‐Deschner, New England Journal of Medicine	2009	842
Active Caspase-1 Is a Regulator of Unconventional Protein Secretion Martin Keller, Andreas Rüegg, Sabine Werner, Cell Protein SecretionProtein FunctionSignal TransductionCell DeathUnconventional Protein Secretion	2008	834
A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses Guangxun Meng, Fuping Zhang, Ivan J. Fuss, Immunity InflammationAutoimmune DiseaseImmunologyImmune RegulationChronic Inflammation	2009	360
In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes Helen J. Lachmann, Philip J. Lowe, Sandra Daniela Felix, The Journal of Experimental Medicine	2009	291
Pattern of interleukin‐1β secretion in response to lipopolysaccharide and ATP before and after interleukin‐1 blockade in patients with <i>CIAS1</i> mutations Marco Gattorno, Sara Tassi, Sonia Carta, Arthritis & Rheumatism	2007	244
Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies Susannah Brydges, Lori Broderick, Matthew D. McGeough, Journal of Clinical Investigation Il-18 Drive PathologyImmunologyImmune RegulationCell DeathPathology	2013	222
IL-Converting Enzyme/Caspase-1 Inhibitor VX-765 Blocks the Hypersensitive Response to an Inflammatory Stimulus in Monocytes from Familial Cold Autoinflammatory Syndrome Patients Jeffrey H. Stack, Kevin Beaumont, Paul D. Larsen, The Journal of Immunology	2005	187

Page 1