Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Michael Kormann, Günther Hasenpusch, Manish K. Aneja, +13

Nature Biotechnology

Protein ExpressionBiochemistryMedicineBiological TherapyGene Delivery +5

Competition between DNA methylation and transcription factors determines binding of NRF1

Silvia Domcke, Anaïs F. Bardet, Paul A. Ginno, +3

Nature

ChromatinNatural SciencesGeneticsDna MethylationEpigenetic Change +9

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

Chun Geun Lee, Dominik Hartl, Gap Ryol Lee, +14

The Journal of Experimental Medicine

Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma

Dominik Hartl, Barbara Koller, Alexander T. Mehlhorn, +5

Journal of Allergy and Clinical Immunology

Clinical ImmunologyAsthmaPediatric AsthmaT-regulatory CellImmunology +4

Chitin regulation of immune responses: an old molecule with new roles

Chun Geun Lee, Carla A. Da Silva, Jaeyoung Lee, +2

Current Opinion in Immunology

InflammationOld MoleculeAutoimmune DiseaseAllergyAdaptive Immune System +9

Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease

Dominik Hartl, Philipp Latzin, Peter L. Hordijk, +9

Nature Medicine

InflammationInflammatory Lung DiseaseNeutrophils DisablesLung InflammationGranulocyte +8

Chitin Is a Size-Dependent Regulator of Macrophage TNF and IL-10 Production

Carla A. Da Silva, Cécile Chalouni, Adam Williams, +3

The Journal of Immunology

Innate Immune SystemImmunologyImmune RegulationLarge Chitin FragmentsImmunologic Mechanism +14

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Franziska Herster, Zsofia Bittner, Nathan K. Archer, +16

Nature Communications

NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatus

Allison McCormick, Leonie Heesemann, Johannes Wagener, +5

Microbes and Infection

PathogenesisImmunologyFungal PhysiologyMicrobiologyMedicine +2

TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation

Carla A. Da Silva, Dominik Hartl, Wei Liu, +2

The Journal of Immunology