Rupert Handgretinger

CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia

Haydar Frangoul, David Altshuler, Maria Domenica Cappellini et al. · New England Journal of Medicine · 2020 · 1.9K citations · Full text

Life Sciences, Genetics, Hematology +17

Human Lymphoid and Myeloid Cell Development in NOD/LtSz- <i>scid IL2R</i> γ <i>null</i> Mice Engrafted with Mobilized Human Hemopoietic Stem Cells,

Leonard D. Shultz, Bonnie Lyons, Lisa Burzenski et al. · The Journal of Immunology · 2005 · 1.7K citations · Full text

Life Sciences, Cell Biology, Immunology +13

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

Isabella Versteege, Nicolas Sévenet, Julian Lange et al. · Nature · 1998 · 1.5K citations

Medicine, Genetics, Oncology +12

Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

Ching-Hon Pui, Dario Campana, Deqing Pei et al. · New England Journal of Medicine · 2009 · 1.2K citations · Full text

Medicine, Oncology, Pediatrics +12

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Michael Kormann, Günther Hasenpusch, Manish K. Aneja et al. · Nature Biotechnology · 2011 · 739 citations

Pharmacy, Molecular Biology, Molecular Pharmaceutics +12