Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

Isabella Versteege, Nicolas Sévenet, Julian Lange, +5

Nature

PathologyCancer GenomicsAggressive Paediatric CancerCancer GeneticsMedicine +1

Recombination between Palindromes P5 and P1 on the Human Y Chromosome Causes Massive Deletions and Spermatogenic Failure

Sjoerd Repping, Helen Skaletsky, Julian Lange, +5

The American Journal of Human Genetics

SpermatogenesisChromatinGenome InstabilityInfertilityGenetics +12

The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair

Julian Lange, Shintaro Yamada, Sam E. Tischfield, +6

Cell

ChromatinGenome InstabilityCell DivisionGeneticsMeiosis +7

ATM controls meiotic double-strand-break formation

Julian Lange, Jing Pan, Francesca Cole, +3

Nature

ChromatinGenome InstabilityCell DivisionNatural SciencesGenetics +8

Homeostatic control of recombination is implemented progressively in mouse meiosis

Francesca Cole, Liisa Kauppi, Julian Lange, +4

Nature Cell Biology

Developmental BiologyGerm CellCell DivisionMedicineGenetics +9

High mutation rates have driven extensive structural polymorphism among human Y chromosomes

Sjoerd Repping, Saskia K.M. van Daalen, Laura Brown, +8

Nature Genetics

High Mutation RatesGenetic DisorderGeneticsEvolutionary BiologyHuman Polymorphism +8

Isodicentric Y Chromosomes and Sex Disorders as Byproducts of Homologous Recombination that Maintains Palindromes

Julian Lange, Helen Skaletsky, Saskia K.M. van Daalen, +7

Cell

ChromatinIsodicentric Y ChromosomesDevelopmental BiologyGenetic DisorderGenetics +11

Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1

Katrin Daniel, Julian Lange, Khaled Hached, +9

Nature Cell Biology

ChromatinDevelopmental BiologyMeiotic Homologue AlignmentCell DivisionGenetics +11

Numerical constraints and feedback control of double-strand breaks in mouse meiosis

Liisa Kauppi, Marco Barchi, Julian Lange, +3

Genes & Development

GeneticsMolecular GeneticsDouble-strand BreaksDsb NumberReproductive Biology +17

Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice

Marcello Stanzione, Marek Baumann, Frantzeskos Papanikos, +10

Nature Cell Biology

ChromatinGenome InstabilityChromosome DynamicsChromatin StructureCell Division +12