Hal M. Hoffman

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao‐Mejia, Eran Elinav, Chengcheng Jin et al. · Nature · 2012 · 2.4K citations

Life Sciences, Immunology, Pathology +12

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

Hal M. Hoffman, James L. Mueller, David H. Broide et al. · Nature Genetics · 2001 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +9

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhenyu Zhong, Atsushi Umemura, Elsa Sánchez‐López et al. · Cell · 2016 · 1.2K citations · Full text

Life Sciences, Cell Biology, Immunology +14

The NLR Gene Family: A Standard Nomenclature

Jenny P.‐Y. Ting, Ruth C. Lovering, Emad S. Alnemri et al. · Immunity · 2008 · 968 citations · Full text

Life Sciences, Genetics, Molecular Genetics +11

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Alexander Wree, Akiko Eguchi, Matthew D. McGeough et al. · Hepatology · 2013 · 934 citations · Full text

Life Sciences, Cell Biology, Immunology +17