Hal M. Hoffman

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao‐Mejia, Eran Elinav, Chengcheng Jin et al. · Nature · 2012 · 2.4K citations

Inflammation, Inflammasome-mediated Dysbiosis, Immunology +6

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

Hal M. Hoffman, James L. Mueller, David H. Broide et al. · Nature Genetics · 2001 · 1.6K citations · Full text

Mendelian Disorder, Disease Mechanism, Genetic Disorder +9

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhenyu Zhong, Atsushi Umemura, Elsa Sánchez‐López et al. · Cell · 2016 · 1.1K citations · Full text

Inflammation, Mitochondrial Function, Immunology +9

The NLR Gene Family: A Standard Nomenclature

Jenny P.‐Y. Ting, Ruth C. Lovering, Emad S. Alnemri et al. · Immunity · 2008 · 962 citations · Full text

Nlr Gene Family, Gene Sequence Annotation, Genetics +6

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Alexander Wree, Akiko Eguchi, Matthew D. McGeough et al. · Hepatology · 2013 · 910 citations · Full text