Targeting Tumor Vasculature With an Oncolytic Virus

Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases

Lenka Grahl, Marie‐Luise von Bruehl, Davit Manukyan et al. · Nature Medicine · 2010 · 1.2K citations

Protease Inhibitors, Inflammation, Autoimmune Disease +11

Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus, and human immunodeficiency virus

Masanori Baba, Robert Snoeck, Rudi Pauwels et al. · Antimicrobial Agents and Chemotherapy · 1988 · 537 citations · Full text

Medicine, Glycobiology, Immunology +13

An Eosinophil-Dependent Mechanism for the Antitumor Effect of Interleukin-4

Robert I. Tepper, Robert L. Coffman, Philip Leder · Science · 1992 · 529 citations

Inflammation, Cytokine, Cancer Immunosurveillance +15

Use of a targeted oncolytic poxvirus, JX-594, in patients with refractory primary or metastatic liver cancer: a phase I trial

Byeong-Ho Park, Tae-Ho Hwang, Ta‐Chiang Liu et al. · The Lancet Oncology · 2008 · 514 citations

Metastatic Liver Cancer, Hepatology, Medicine +9

Targeted Inflammation During Oncolytic Virus Therapy Severely Compromises Tumor Blood Flow

Caroline J. Breitbach, Jennifer M Paterson, Chantal G. Lemay et al. · Molecular Therapy · 2007 · 274 citations · Full text