Concepedia

Systemic Virus Administration

Systemic Virus Administration is a method of delivering oncolytic viruses into the bloodstream to enable widespread distribution throughout the body for targeting metastatic tumors, distinguished from localized delivery approaches by its capacity to reach disseminated cancer lesions via circulatory pathways.

254

Publications

15.7K

Citations

1.8K

Authors

458

Institutions

Publications per year

2017–2026

55

Parents

Publications

254

A Phase I Study of OncoVEXGM-CSF, a Second-Generation Oncolytic Herpes Simplex Virus Expressing Granulocyte Macrophage Colony-Stimulating Factor

Jennifer Hu, Robert S. Coffin, C. J. Davis et al. · Clinical Cancer Research · 2006 · 568 citations

, , +16

Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons

Sandra Duqué, Béatrice Joussemet, Christel Rivière et al. · Molecular Therapy · 2009 · 497 citations · Full text

, , +17

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

Adel Samson, Karen J. Scott, David J. Taggart et al. · Science Translational Medicine · 2018 · 377 citations · Full text

, , +17

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication†

Karin S. Blanchard, Lucinda Shaw, Kristi Jensen et al. · Hepatology · 2005 · 291 citations · Full text

, , +17

Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy

Stephen J. Russell, Mark J. Federspiel, Kah-Whye Peng et al. · Mayo Clinic Proceedings · 2014 · 272 citations

, , +14

1–5 of 254

Authors

1.8K

  1. SJ
    Stephen J. Russell

    Mayo Clinic, United States

    19 publications · 1.5K citations

    18

    h-index

  2. MJ
    Mark J. Federspiel

    Mayo Clinic, United States

    12 publications · 1.1K citations

    12

    h-index

  3. RG
    Richard G. Vile

    Mayo Clinic, United States

    10 publications · 1.2K citations

    10

    h-index

  4. KJ
    Kevin J. Harrington

    Institute of Cancer Research, United Kingdom

    10 publications · 1.7K citations

    10

    h-index

  5. AM
    Alan Melcher

    Institute of Cancer Research, United Kingdom

    9 publications · 1.2K citations

    9

    h-index

1–5 of 1.8K

Institutions

458

  1. Mayo Clinic

    Rochester, United States

    22 h-index

    145 publications

    11.5K citations

  2. Mayo Clinic in Arizona

    Scottsdale, United States

    16 h-index

    76 publications

    8.5K citations

  3. Mayo Clinic in Florida

    Jacksonville, United States

    10 h-index

    17 publications

    763 citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    10 h-index

    36 publications

    1.4K citations

  5. University of California San Diego

    San Diego, United States

    9 h-index

    34 publications

    1.3K citations

  6. WinnMed

    Decorah, United States

    9 h-index

    29 publications

    3.2K citations

  7. Harvard University

    Cambridge, United States

    8 h-index

    26 publications

    1.6K citations

  8. Icahn School of Medicine at Mount Sinai

    New York, United States

    8 h-index

    23 publications

    1.3K citations

1–8 of 458

Venues

  1. Molecular Therapy

    32 publications · 2.4K citations

    25

    h-index

  2. Human Gene Therapy

    20 publications · 1.2K citations

    17

    h-index

  3. Clinical Cancer Research

    14 publications · 1.5K citations

    14

    h-index

  4. Gene Therapy

    12 publications · 647 citations

    12

    h-index

  5. PubMed

    Repository · 11 publications · 633 citations

    11

    h-index

1–5