Alan Melcher

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies

Frederick Arce Vargas, Andrew J.S. Furness, Kevin Litchfield et al. · Cancer Cell · 2018 · 585 citations · Full text

Medicine, Immunology, Oncology +17

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

Alan Melcher, Stephen Todryk, Nicola Hardwick et al. · Nature Medicine · 1998 · 444 citations

Medicine, Immunology, Oncology +16

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

Adel Samson, Karen J. Scott, David J. Taggart et al. · Science Translational Medicine · 2018 · 377 citations · Full text

Medicine, Immunology, Oncology +17

Heat Shock Protein 70 Induced During Tumor Cell Killing Induces Th1 Cytokines and Targets Immature Dendritic Cell Precursors to Enhance Antigen Uptake

Stephen Todryk, Alan Melcher, Nicola Hardwick et al. · The Journal of Immunology · 1999 · 333 citations · Full text

Life Sciences, Immunology, Oncology +17

A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer

Laura Vidal, Hardev Pandha, Timothy A. Yap et al. · Clinical Cancer Research · 2008 · 239 citations

Life Sciences, Immunology, Oncology +17