Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

Adel Samson, Karen J. Scott, David J. Taggart, +36

Science Translational Medicine

Anti–PD-1/anti–CTLA-4 efficacy in melanoma brain metastases depends on extracranial disease and augmentation of CD8⁺T cell trafficking

David J. Taggart, Tereza Andreou, Karen J. Scott, +7

Proceedings of the National Academy of Sciences

Cell Carriage, Delivery, and Selective Replication of an Oncolytic Virus in Tumor in Patients

Robert A. Adair, Victoria Roulstone, Karen J. Scott, +22

Science Translational Medicine

Viral ReplicationImmunologyPathologyVivo Immune EvasionImmunotherapy +16

Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

Robin Prestwich, Fiona Errington‐Mais, Elizabeth J. Ilett, +10

Clinical Cancer Research

Measles virus causes immunogenic cell death in human melanoma

Oliver Donnelly, Fiona Errington‐Mais, Lynette P. Steele, +12

Gene Therapy

Human MelanomaMelanomaImmunologyPathologyVirology +2

Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma

Charles L. White, Katie Twigger, Ailsa Rose, +10

Gene Therapy

Inflammatory Tumour CellMelanomaImmunologyVirologyOncolytic Reovirus +7

Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer

Adel Samson, Matthew Bentham, Karen J. Scott, +15

Gut

Perioperative Influenza Vaccination Reduces Postoperative Metastatic Disease by Reversing Surgery-Induced Dysfunction in Natural Killer Cells

Lee‐Hwa Tai, Jiqing Zhang, Karen J. Scott, +11

Clinical Cancer Research

Cytotoxic and immune‐mediated killing of human colorectal cancer by reovirus‐loaded blood and liver mononuclear cells

Robert A. Adair, Karen J. Scott, Sheila Fraser, +9

International Journal of Cancer

Viral PathogenesisImmunologyPathologyNk CellsImmunoediting +18

Aspirin-Treated Human DCs Up-Regulate ILT-3 and Induce Hyporesponsiveness and Regulatory Activity in Responder T Cells

Matthew Buckland, Charlotte Jago, Henrieta Fazekasova, +4

American Journal of Transplantation