Caroline J. Breitbach

Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

Jeong Heo, Tony Reid, Leyo Ruo et al. · Nature Medicine · 2013 · 776 citations · Full text

Medicine, Immunology, Oncology +16

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

Caroline J. Breitbach, James M. Burke, Derek J. Jonker et al. · Nature · 2011 · 550 citations

Pharmacy, Oncology, Pharmaceutics +12

Translational control of the innate immune response through IRF-7

Rodney Colina, Mauro Costa‐Mattioli, Ryan J.O. Dowling et al. · Nature · 2008 · 313 citations · Full text

Life Sciences, Immunology, Molecular Genetics +14

The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers

Kelley A. Parato, Caroline J. Breitbach, Jiahu Wang et al. · Molecular Therapy · 2011 · 308 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Targeted Inflammation During Oncolytic Virus Therapy Severely Compromises Tumor Blood Flow

Caroline J. Breitbach, Jennifer M Paterson, Chantal G. Lemay et al. · Molecular Therapy · 2007 · 277 citations · Full text

Medicine, Cancer Biology, Oncology +17