SillaJen (South Korea)

Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

Jeong Heo, Tony Reid, Leyo Ruo et al. · Nature Medicine · 2013 · 753 citations · Full text

Vaccination, Dose-finding Clinical Trial, Hepatology +12

Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer

Se Hoon Park, Caroline J. Breitbach, Jeeyun Lee et al. · Molecular Therapy · 2015 · 174 citations · Full text

Phase 1 Study of Intratumoral Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus, in Pediatric Cancer Patients

Timothy P. Cripe, Minhtran Ngo, James I. Geller et al. · Molecular Therapy · 2014 · 156 citations · Full text

First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity

Herbert J. Zeh, Stephanie Downs‐Canner, J. Andrea McCart et al. · Molecular Therapy · 2014 · 150 citations · Full text

Oncolytic and Immunotherapeutic Vaccinia Induces Antibody-Mediated Complement-Dependent Cancer Cell Lysis in Humans

Mi Kyung Kim, Caroline J. Breitbach, Anne Moon et al. · Science Translational Medicine · 2013 · 101 citations