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In vitro characterisation of the novel positive allosteric modulators of the mGlu5 receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat

Molecular PharmacologySleepVitro CharacterisationMolecular NeuroscienceSignal TransductionMolecular PhysiologyG Protein-coupled ReceptorMedicineFunctional SelectivityPhysiologyReceptor (Biochemistry)NeuropharmacologySleep ArchitectureMglu5 ReceptorExperimental PharmacologyPharmacologyCell SignalingMelatonin