Concepedia

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication

Peng Wang, Juan Carlos Álvarez-Pérez, Dan P. Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sánchez, Donald K. Scott, Adolfo Garcı́a-Ocaña,

Nature Medicine · 2015 · 404 citations · 40 references

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40

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Ji-Hu Zhang, Thomas D.Y. Chung, Kevin R. Oldenburg · SLAS DISCOVERY · 1999 · 7K citations · Full text

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β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

, , +17

β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in Humans

Juris J. Meier, Alexandra E. Butler, Yoshifumi Saisho et al. · Diabetes · 2008 · 686 citations · Full text

, , +17

Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression

Stella Pelengaris, Michael Khan, Gérard I. Evan · Cell · 2002 · 628 citations · Full text

, , +14

Genetic Analysis of Italian Patients with Congenital Hyperinsulinism of Infancy

Paola Sogno Valin, Maria Carla Proverbio, Cecilia Diceglie et al. · Hormone Research in Paediatrics · 2013 · 554 citations

, , +16