Juan Carlos Álvarez-Pérez

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication

Peng Wang, Juan Carlos Álvarez-Pérez, Dan P. Felsenfeld et al. · Nature Medicine · 2015 · 394 citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +7

Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus

Cem Demirci, Sara Ernst, Juan Carlos Álvarez-Pérez et al. · Diabetes · 2012 · 113 citations · Full text

Immune Regulation, Cell Death, Pancreatic β-Cells Leads +16

FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice

Ting Zhang, Dae Hyun Kim, Xiangwei Xiao et al. · Endocrinology · 2016 · 82 citations · Full text

Hepatocyte Growth Factor/c-Met Signaling Is Required for β-Cell Regeneration

Juan Carlos Álvarez-Pérez, Sara Ernst, Cem Demirci et al. · Diabetes · 2013 · 71 citations · Full text

Regenerative Medicine, Glucose Tolerance, Islet Transplantation +15

Glucose-dependent partitioning of arginine to the urea cycle protects β-cells from inflammation

Accalia Fu, Juan Carlos Álvarez-Pérez, Daina Avizonis et al. · Nature Metabolism · 2020 · 61 citations · Full text

Inflammation, Urea Cycle, Cell Signaling +12