The Journal of Antibiotics · 1979 · 13 citations · 11 references
Life SciencesMicrobiologyMicrobial MetabolismNatural Product BiosynthesisAmino Acid FermentationAntibiotic FermentationAntibiotic ProductionBacterial FermentationMicrobial Metabolite ProductionMicrobial Natural Product BiosynthesisAntimicrobial MetabolitesAntimicrobial Peptide ProductionBacteriocin ProductionBacteriocins In FoodsProduction Of Antimicrobial Compounds
The conversion of fortimicin E, a minor metabolite from the Micromonospora olivoasterospora fermentation which also produces fortimicin A and fortimicin B, to four 4-N-aminoacylfortimicins E was accomplished. The new 4-N-aminoacylfortimicins E showed only weak antimicrobial activity against several Gram-negative and Gram-positive microorganisms.
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