Concepedia

Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement

Ismail Moarefi, Michelle LaFevre-Bernt, Frank Sicheri, Morgan Huse, Chi‐Hon Lee, John Kuriyan, W. Todd Miller

Nature · 1997 · 606 citations · 20 references

DOI

Concepts

References

20

Crystal structure of the Src family tyrosine kinase Hck

Frank Sicheri, Ismail Moarefi, John Kuriyan · Nature · 1997 · 1.2K citations

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Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions

Sibo Feng, James Chen, Hongtao Yu et al. · Science · 1994 · 807 citations

, , +17

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

Thomas E. Kmiecik, David Shalloway · Cell · 1987 · 645 citations

, , +11

Proline‐rich (PxxP) motifs in HIV‐1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down‐regulation of CD4.

Kalle Saksela, Genhong Cheng, David Baltimore · The EMBO Journal · 1995 · 555 citations · Full text

, , +15

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

Helen Piwnica‐Worms, Kim B. Saunders, Thomas M. Roberts et al. · Cell · 1987 · 538 citations

, , +11