Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

Peter J. Southern, Paul Berg · PubMed · 1982 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +17

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

Tony Hunter, Bartholomew M. Sefton · Proceedings of the National Academy of Sciences · 1980 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

Leland Ellis, Éric Clauser, David O. Morgan et al. · Cell · 1986 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +14

Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

Tatsuo Takeya, Hidesaburô Hanafusa · Cell · 1983 · 585 citations

Life Sciences, Genetics, Molecular Biology +15

Tyr ⁵²⁷ Is Phosphorylated in pp60 ^{c- <i>src</i>} : Implications for Regulation

Jonathan A. Cooper, Kathleen L. Gould, Christine A. Cartwright et al. · Science · 1986 · 549 citations

Life Sciences, Biochemistry, Molecular Biology +14