Kalle Saksela

Decay characteristics of HIV-1-infected compartments during combination therapy

Alan S. Perelson, Paulina Essunger, Yunzhen Cao et al. · Nature · 1997 · 1.9K citations

Decay Characteristics, Human Retrovirus, Immunology +7

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.

Kalle Saksela, Genhong Cheng, David Baltimore · The EMBO Journal · 1995 · 553 citations · Full text

Viral Replication, Signal Transduction, Human Retrovirus +10

Crystal Structure of the Conserved Core of HIV-1 Nef Complexed with a Src Family SH3 Domain

Chi‐Hon Lee, Kalle Saksela, Urooj A. Mirza et al. · Cell · 1996 · 433 citations · Full text

Conserved Core, Virus Structure, Crystal Structure +10

A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.

Chi‐Hon Lee, Bonnie W. Leung, Mark A. Lemmon et al. · The EMBO Journal · 1995 · 256 citations · Full text

Virus Structure, Viral Replication, Biochemistry +12

Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses

Benjamin K. Chen, Kalle Saksela, Raul Andino et al. · Journal of Virology · 1994 · 203 citations · Full text

Viral Replication, Distinct Modes, Immunology +16