Publication | Open Access

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.

Viral ReplicationSignal TransductionHuman RetrovirusHiv-1 Nef BindAntiviral ResponseMolecular BiologySrc KinasesHivViral Structural ProteinMedicineCell BiologyCell SignalingNef+ Viruses