Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

Aihao Ding, Carl Nathan, Dennis J. Stuehr · The Journal of Immunology · 1988 · 2.8K citations · Full text

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

Brian S. Andrews, Robert A. Eisenberg, Argyrios N. Theofilopoulos et al. · The Journal of Experimental Medicine · 1978 · 1.6K citations · Full text

Immunopathological Manifestations, Immunology, Pathology +18

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

Ignacio Melero, Walter W. Shuford, S A Newby et al. · Nature Medicine · 1997 · 883 citations

Tumor Immunology, Cancer Immunosurveillance, T-regulatory Cell +8

4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

Walter W. Shuford, Kerry Klussman, Douglas D. Tritchler et al. · The Journal of Experimental Medicine · 1997 · 787 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +17

Treatment of Murine Lupus with CTLA4Ig

Peter S. Linsley, David Wofsy · Science · 1994 · 667 citations