Concepedia

Lymphocyte Costimulation

Lymphocyte Costimulation is a biological process in which secondary, non-antigen-specific signals are provided to lymphocytes alongside primary antigen recognition to fully activate adaptive immune responses, thereby distinguishing it from antigen-independent or solo stimulatory mechanisms within immune activation pathways.

72

Publications

7.1K

Citations

354

Authors

140

Institutions

Publications per year

2017–2026

3

Parents

Publications

72

T Lymphocyte Costimulation Mediated by Reorganization of Membrane Microdomains

Antonella Viola, Susanne Schroeder, Yoichi Sakakibara et al. · Science · 1999 · 941 citations

, , +17

JNK is involved in signal integration during costimulation of T lymphocytes

Bing Su, Estela Jacinto, Masahiko Hibi et al. · Cell · 1994 · 921 citations

, , +14

“Lymphokines”: Non-Antibody Mediators of Cellular Immunity generated by Lymphocyte Activation

D. C. Dumonde, R. A. Wolstencroft, G. S. Panayi et al. · Nature · 1969 · 577 citations

, , +16

Genetically Targeted T Cells Eradicate Systemic Acute Lymphoblastic Leukemia Xenografts

Renier J. Brentjens, Elmer Santos, Yan Nikhamin et al. · Clinical Cancer Research · 2007 · 466 citations

, , +17

Blockade of T Lymphocyte Costimulation with Cytotoxic T Lymphocyte–Associated Antigen 4–Immunoglobulin (Ctla4ig) Reverses the Cellular Pathology of Psoriatic Plaques, Including the Activation of Keratinocytes, Dendritic Cells, and Endothelial Cells

Judith R. Abrams, Susan L. Kelley, Elizabeth Hayes et al. · The Journal of Experimental Medicine · 2000 · 319 citations · Full text

, , +17

1–5 of 72

Authors

354

  1. LC
    Leonard Chess

    Columbia University, United States

    6 publications · 453 citations

    6

    h-index

  2. SF
    Stuart F. Schlossman

    Dana-Farber Cancer Institute, United States

    6 publications · 453 citations

    6

    h-index

  3. RP
    Richard P. MacDermott

    Washington University in St. Louis, United States

    5 publications · 434 citations

    5

    h-index

  4. VL
    Vincent Ling

    Harvard University, United States

    3 publications · 288 citations

    3

    h-index

  5. VP
    Verner Paetkau

    University of Alberta, Canada

    3 publications · 314 citations

    3

    h-index

1–5 of 354

Institutions

140

  1. Harvard University

    Cambridge, United States

    8 h-index

    23 publications

    1.7K citations

  2. Dana-Farber Cancer Institute

    Boston, United States

    5 h-index

    16 publications

    725 citations

  3. Hammersmith Hospital

    London, United Kingdom

    3 h-index

    7 publications

    322 citations

  4. UPMC Hillman Cancer Center

    Pittsburgh, United States

    3 h-index

    11 publications

    845 citations

  5. Inserm

    Paris, France

    3 h-index

    15 publications

    307 citations

  6. University of Alberta

    Edmonton, Canada

    3 h-index

    11 publications

    1.2K citations

  7. Cancer Research Institute

    New York, United States

    3 h-index

    6 publications

    674 citations

  8. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    5 publications

    933 citations

1–8 of 140

Venues

  1. The Journal of Immunology

    JI · 11 publications · 1K citations

    11

    h-index

  2. PubMed

    Repository · 4 publications · 179 citations

    4

    h-index

  3. Clinical Immunology and Immunopathology

    4 publications · 93 citations

    4

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 342 citations

    4

    h-index

  5. Human Immunology

    3 publications · 76 citations

    3

    h-index

1–5