Concepedia

Serum interleukin-10 levels in patients with advanced gastrointestinal malignancies

Ferdinando De Vita, Michele Orditura, Gennaro Galizia, Ciro Romano, Stefania Infusino, Annunziata Auriemma, Eva Lieto, Giuseppe Catalano

Cancer · 1999 · 91 citations · 29 references

DOIFull text

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Abstract

The results of the current study show that measurement of pretreatment serum levels of IL-10 is of independent prognostic utility in patients with advanced gastrointestinal carcinoma and may be useful for the detection of disease progression.

References

29

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

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Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

Lieping Chen, Stephanie Ashe, William Brady et al. · Cell · 1992 · 1.1K citations

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Human interleukin-10 can directly inhibit T-cell growth

K Taga, H Mostowski, Giovanna Tosato · Blood · 1993 · 279 citations · Full text

Serum interleukin-10 in non-Hodgkin's lymphoma: a prognostic factor

Nicolas Burdin, F Rousset, Gilbert Lenoir et al. · Blood · 1993 · 239 citations · Full text

Interleukin-10 prevents dendritic cell accumulation and vaccination with granulocyte-macrophage colony-stimulating factor gene-modified tumor cells

Zhihai Qin, Gabriele Noffz, Mariette Mohaupt et al. · The Journal of Immunology · 1997 · 198 citations · Full text