MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Ruthie E. Amir, Ignatia B. Van den Veyver, Mimi Wan et al. · Nature Genetics · 1999 · 5K citations

Chromatin, Genome Instability, Transcriptional Regulation +11

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

Histone Modifications, Chromatin, Transcriptional Regulation +13

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

Maria H. Chahrour, Sung Yun Jung, Chad A. Shaw et al. · Science · 2008 · 1.8K citations · Full text

Genetics, Mecp2 Gene Cause, Key Contributor +25

Transition from Moderate to Excessive Drug Intake: Change in Hedonic Set Point

Serge H. Ahmed, George F. Koob · Science · 1998 · 1.2K citations

Substance Use, Behavioral Addiction, Drug Treatment +19

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

Ngan Vo, Matthew Klein, Olga Varlamova et al. · Proceedings of the National Academy of Sciences · 2005 · 795 citations · Full text

Camp-response Element, Cellular Neurobiology, Neuronal Morphogenesis +16